Methyltetrazine-PEG4-SS-PEG4-methyltetrazine
HY-130943
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameMethyltetrazine-PEG4-SS-PEG4-methyltetrazine
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC48H70N12O12S2
- Molecular Weight1071.27
- Scientific DescriptionMethyltetrazine-PEG4-SS-PEG4-methyltetrazine is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
- SMILESO=C(CCOCCOCCOCCOCCNC(CCSSCCC(NCCOCCOCCOCCOCCC(NCC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O)=O)=O)NCC3=CC=C(C4=NN=C(C)N=N4)C=C3
- UNSPSC41115800