MFSD2A antibody

GeneTex

MFSD2A antibody

9

WB: 1 - 2 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

MFSD2A

major facilitator superfamily domain containing 2A

major facilitator superfamily domain-containing protein 2A; MCPH15; MFSD2; NEDMISBA; NLS1; SLC59A1; sodium-dependent LPC symporter 1; sodium-dependent lysophosphatidylcholine symporter 1

Rabbit

IgG

Sodium-dependent lysophosphatidylcholine symporter 1

Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts. MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203