mGluR2 + mGluR3 antibody

GeneTex

mGluR2 + mGluR3 antibody

9

Reacts with residues 860-872 [NGREVVDSTTSSL] of the rat mGlurR2/3 protein. Sequence is 100% conserved between mGluR2 and mGluR3. Predicted react to human and mouse.

Recommended Starting Dilutions:For WB: Use at 1:500 dilutionFor ICC/IF: Use at 1:250 For IHC: Use at 1:250 Not yet tested in other applications. Optimal dilutions should be determined experimentally by the researcher.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Rabbit

IgG

Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.

Rat

-20°C or -80°C,2°C to 8°C

12352203