mGluR2 modulator 5
HY-168028
Molecular Weight386.37
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NamemGluR2 modulator 5
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC20H17F3N4O
- Molecular Weight386.37
- Scientific DescriptionmGluR2 modulator 5 (Compound 11) is an orally active, selective mGluR2 negative allosteric modulator with an IC50 of 8.9 nM. Pharmacokinetic studies in rats show that mGluR2 modulator 5 can effectively cross the blood-brain barrier. It can modulate cognitive and neurological functions in mood disorders and is suitable for research in the field of neurodegenerative diseases[1].
- SMILESCC1=NC=CC(C2=C(C(N(C3=CC=C(C(F)(F)F)C=C3)C[C@@H]4C)=O)N4N=C2)=C1
- UNSPSC12352200