MGME1 Antibody, Biotin conjugated

Cusabio

MGME1 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

Rabbit

IgG

Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5\-3\ exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.

Human

-20°C or -80°C

12352203