Western blot analysis of extracts from Jurkat cells, using MGMT antibody.
Western blot analysis of extracts from Jurkat cells, using MGMT antibody.
MGMT Antibody
CSB-PA563873
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Rat
TargetMGMT
Overview
- SupplierCusabio
- Product NameMGMT Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4255
- Target nameMGMT
- Target descriptionO-6-methylguanine-DNA methyltransferase
- Target synonyms6-O-methylguanine-DNA methyltransferase; methylated-DNA--protein-cysteine methyltransferase; methylguanine-DNA methyltransferase; O6-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase
- HostRabbit
- IsotypeIgG
- Protein IDP16455
- Protein NameMethylated-DNA--protein-cysteine methyltransferase
- Scientific DescriptionInvolved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Tano K., Proc. Natl. Acad. Sci. U.S.A. 87:686-690(1990). Rydberg B., J. Biol. Chem. 265:9563-9569(1990). Koike G., J. Biol. Chem. 265:14754-14762(1990)
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203