MHC II (HLA-DRA)(169-1B5.2), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

MHC II (HLA-DRA)(169-1B5.2), CF405S conjugate, 0.1mg/mL

9

Flow Cytometry, ImmunoFluorescence

Research Use Only

Monoclonal

169-1B5.2

0.1 mg/ml

Other Conjugate

HLA-DRA

major histocompatibility complex, class II, DR alpha

histocompatibility antigen HLA-DR alpha; HLA class II histocompatibility antigen, DR alpha chain; HLA-DRA1; MHC class II antigen DRA

Mouse

IgG2b

HLA class II histocompatibility antigen, DR alpha chain

This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Feline, Human, Mouse

2°C to 8°C

12352203