MI-219

MedChem Express

MI-219

5

Research Use Only

C27H32Cl2FN3O4

552.47

MI-219 is an antagonist for MDM2 with a Ki of 13.3 microM. MI-219 inhibits the MDM2-p53 interaction, inhibits thus the proliferation of FSCCL cells, with an IC50 of 2.5 microM[1].

O=C([C@H](N[C@@H]1CC(C)(C)C)[C@H](C2=CC=CC(Cl)=C2)[C@]31C(NC4=C3C=C(F)C(Cl)=C4)=O)NCC[C@H](O)CO

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