Mib antibody

GeneTex

Mib antibody

9

IHC-Wm: 1:50-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

mib1

MIB E3 ubiquitin protein ligase 1

cg5841; chunp68; chunp6889; E3 ubiquitin-protein ligase mib1; fe47f05; im:714810; im:7148100; mi; mib; mind bomb; mindbomb E3 ubiquitin protein ligase 1; protein mind bomb; RING-type E3 ubiquitin transferase mib1; white tail; wi; wit; wu:fe47f05

Rabbit

IgG

E3 ubiquitin-protein ligase mib1

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It thereby participates in many processes regulated by the Notch signaling pathway, such as midline cell fate specification prior to germ layer formation, patterning of sensory cell differentiation in the ear, neurogenesis of the hindbrain and commitment to a secretory fate in the intestine. Essential for early embryonic development.

Zebra Fish

-20°C or -80°C,2°C to 8°C

12352203