Bio-Connect

MIB1 Polyclonal Antibody

RD85199A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMIB1
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    MIB1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID57534
  • Target name
    MIB1
  • Target description
    MIB E3 ubiquitin protein ligase 1
  • Target synonyms
    DAPK-interacting protein 1; DIP1; DIP-1; E3 ubiquitin-protein ligase MIB1; LVNC7; MIB; mindbomb E3 ubiquitin protein ligase 1; RING-type E3 ubiquitin transferase MIB1; ubiquitin ligase mind bomb; zinc finger ZZ type with ankyrin repeat domain protein 2; ZZANK2; ZZZ6
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203