MICAL2 Antibody, FITC conjugated

Cusabio

MICAL2 Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

MICAL2

microtubule associated monooxygenase, calponin and LIM domain containing 2

[F-actin]-methionine sulfoxide oxidase MICAL2; [F-actin]-monooxygenase MICAL2; Ebitein1; ebitein-1; ERK2-binding testicular protein 1; flavoprotein oxidoreductase MICAL2; MICAL C-terminal like; MICAL C-terminal-like protein; MICAL-2; MICAL2PV1; MICAL2PV2; MICALCL; mical-cL; microtubule associated monoxygenase, calponin and LIM domain containing 2; molecule interacting with CasL protein 2; protein-methionine sulfoxide oxidase MICAL2

Rabbit

IgG

[F-actin]-monooxygenase MICAL2

Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the SRF signaling. Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.

Human

-20°C or -80°C

12352203