Milademetan tosylate hydrate

Biorbyt

Milademetan tosylate hydrate [2095625-97-9]

10

2095625-97-9

Research Use Only

98.00%

C37H44Cl2FN5O8S

808.74

Milademetan (DS-3032) tosylate hydrate, an orally active and specific MDM2 inhibitor, is utilized in the study of acute myeloid leukemia (AML) and solid tumors. It induces G1 cell cycle arrest, senescence, and apoptosis, showcasing its therapeutic potential [1] [2].

S(=O)(=O)(O)C1=CC=C(C)C=C1.O=C1[C@@]2(C3(N[C@@H](C(N[C@@H]4CC[C@@H](C(N)=O)OC4)=O)[C@@H]2C=5C(F)=C(Cl)N=CC5)CCC(C)(C)CC3)C=6C(N1)=CC(Cl)=CC6.O

-20°C

12352200