More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Milciclib (maleate)

Milciclib (maleate)

HY-10424A
MedChem Express
Molecular Weight576.65
Product group Chemicals
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    MedChem Express
  • Product Name
    Milciclib (maleate)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C29H36N8O5
  • Molecular Weight
    576.65
  • Scientific Description
    Milciclib (PHA-848125) maleate is a cyclin-dependent kinase inhibitor that impairs melanoma cell growth and modulates gene expression involved in cell cycle regulation. Milciclib maleate has been shown to significantly affect the expression of various genes, including down-regulating PTTG1, contributing to its antiproliferative activity. Milciclib maleate enhances sensitivity to treatment in p53 mutated melanoma cells when combined with PTTG1 silencing.
  • SMILES
    O=C(NC)C1=NN(C2=C1C(C)(CC3=CN=C(N=C23)NC4=CC=C(C=C4)N5CCN(CC5)C)C)C.OC(/C=C\C(O)=O)=O
  • UNSPSC
    12352200