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Mirin

HY-117693
MedChem Express
CAS Number299953-00-7
DownloadMSDS
Product group Chemicals
Estimated Purity98.12
Molecular Weight220.25
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Mirin [299953-00-7]
  • Delivery Days Customer
    10
  • CAS Number
    299953-00-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.12
  • Molecular Formula
    C10H8N2O2S
  • Molecular Weight
    220.25
  • Scientific Description
    Mirin is a potent Mre11-Rad50-Nbs1 (MRN) complex inhibitor. Mirin prevents MRN-dependent activation of ATM (IC 50 =12 microM) without affecting ATM protein kinase activity, and it inhibits Mre11-associated exonuclease activity. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells. Mirin prevents ATM activation in response to DNA double-strand breaks (DSBs) and blocks homology-directed repair (HDR) in mammalian cells [1] .
  • SMILES
    O=C1N=C(N)S/C1=C/C2=CC=C(O)C=C2
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200