Mitapivat (hemisulfate sesquihydrate)

MedChem Express

Mitapivat (hemisulfate sesquihydrate)

9

Research Use Only

C24H26N4O3S.1/2H2SO4.3/2H2O

526.62

Mitapivat hemisulfate sesquihydrate (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase) -deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency [1] [2] [3] .

O=C(N1CCN(CC2CC2)CC1)C3=CC=C(NS(=O)(C4=CC=CC5=CC=CN=C54)=O)C=C3.O=S(O)(O)=O.O.[0.5].[1.5]

12352200