Immunohistochemical staining using microphthalmia antibody on formalin ?xed, paraf?n embedded human melanoma.
Immunohistochemical staining using microphthalmia antibody on formalin ?xed, paraf?n embedded human melanoma.
MITF antibody [C5]
GTX12039
ApplicationsGel Shift Assay, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMITF
Overview
- SupplierGeneTex
- Product NameMITF antibody [C5]
- Delivery Days Customer9
- Application Supplier NoteFor IP: Use at a concentration of 2 microg/ml. For WB: Use at a concentration of 1 microg/ml. Optimal dilutions/concentrations should be determined by the researcher.
- ApplicationsGel Shift Assay, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDC5
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4286
- Target nameMITF
- Target descriptionmelanocyte inducing transcription factor
- Target synonymsbHLHe32; class E basic helix-loop-helix protein 32; CMM8; COMMAD; melanogenesis associated transcription factor; MI; microphtalmia-associated transcription factor; microphthalmia-associated transcription factor; MITF-A; WS2; WS2A
- HostMouse
- IsotypeIgG1
- Protein IDO75030
- Protein NameMicrophthalmia-associated transcription factor
- Scientific DescriptionThe protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin-like protease(s) in a subpopulation of microglia in neonatal rat brain. Kawahara K et al., 2016 Nov, GliaRead more