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ProductsBack/Mitotane-13C6 [1261396-21-7]

Mitotane-13C6 [1261396-21-7]

HY-13690S1
MedChem Express
CAS Number1261396-21-7
DownloadMSDS
Product group Chemicals
Estimated Purity98.62
Molecular Weight326.00
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Mitotane-13C6 [1261396-21-7]
  • Delivery Days Customer
    10
  • CAS Number
    1261396-21-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.62
  • Molecular Formula
    C8 13C6H10Cl4
  • Molecular Weight
    326.00
  • Scientific Description
    Mitotane-13C6 is the 13C labeled Mitotane[1]. Mitotane (2,4-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[2][3][4][5].
  • SMILES
    ClC(Cl)C([13C]1=[13CH][13CH]=[13C]([13CH]=[13CH]1)Cl)C2=C(C=CC=C2)Cl
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12131703