MK-3577

MedChem Express

MK-3577

9

Research Use Only

C30H30ClFN2O3

521.02

MK-3577 is an orally effective glucagon receptor ( GCGR ) antagonist that reduces hepatic glucose production and lowers blood glucose levels by blocking glucagon receptors on target organs, primarily the liver. Pharmacokinetic analysis in domestic cats indicates that MK-3577 reaches peak levels 3 to 4 hours after oral administration, with a half-life of approximately 15 hours. MK-3577 can be used in diabetes research [1] .

CCC[C@H](C1=CC=C(C=C1)C(NCCC(O)=O)=O)[C@H](C2=CC=C(C=C2)Cl)C(C3=CC(C)=C4)=CNC3=C4F

12352200