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Chemical Structure
Chemical Structure
Chemical Structure

MK-571 . sodium salt [115103-85-0]

Research Use Only
AG-CR1-0021
AdipoGen Life Sciences
CAS Number115103-85-0
Product group Chemicals
Estimated Purity>97%
Molecular Weight514.1 . 23.0
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Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    MK-571 . sodium salt [115103-85-0, 115104-28-4]
  • Delivery Days Customer
    10
  • CAS Number
    115103-85-0
  • Certification
    Research Use Only
  • Estimated Purity
    >97%
  • Hazard Information
    Warning
  • Molecular Formula
    C26H26ClN2O3S2 . Na
  • Molecular Weight
    514.1 . 23.0
  • Scientific Description
    Chemical. CAS: 115103-85-0 - 115104-28-4 (free base). Formula: C26H26ClN2O3S2 . Na. MW: 514.1 . 23.0. Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor. Antinociceptive. - Selective leukotriene LTD4 receptor antagonist [1]. Potent multidrug resistance-associated protein MRP1 and MRP2 inhibitor [2,4]. Antinociceptive [3].
  • SMILES
    [Na+].CN(C)C(=O)CCSC(SCCC([O-])=O)C1=CC(\C=C\C2=CC=C3C=CC(Cl)=CC3=N2)=CC=C1
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist: T.R. Jones, et al.; Can. J. Physiol. Pharmacol. 67, 17 (1989)
  • The leukotriene LTD4 receptor antagonist MK571 specifically modulates MRP associated multidrug resistance: V. Gekeler, et al.; BBRC 208, 345 (1995)
  • The antinociceptive effect of leukotriene D(4) receptor antagonist, MK-571, in mice: possible involvement of opioidergic mechanism: Eur. J. Pharmacol. 386, 195 (1999)