MK2-IN-1 (hydrochloride)

MedChem Express

MK2-IN-1 (hydrochloride) [1314118-94-9]

10

1314118-94-9

Research Use Only

98.36

C27H26Cl2N4O2

509.43

MK2-IN-1 hydrochloride (compound 1) is a potent and selecitve MAPKAPK2 (MK2) inhibitor with an IC 50 of 0.11 uM for MK2 and an EC 50 of 0.35 uM for pHSP27. MK2-IN-1 hydrochloride impaires the phosphorylation level of serine residues in the Tfcp2l1 protein [1] [2] .

O=C(C1=CC=C(C2=CC=C(Cl)C=C2)O1)N(C3=CC=C(N4CCNCC4)C=C3)CC5=NC=CC=C5.[H]Cl

2°C to 8°C

12352200