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MKRN1 antibody

Research Use Only
ORB67219
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetMKRN1
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Overview

  • Supplier
    Biorbyt
  • Product Name
    MKRN1 antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID23608
  • Target name
    MKRN1
  • Target description
    makorin ring finger protein 1
  • Target synonyms
    E3 ubiquitin-protein ligase makorin-1; RING finger protein 61; RING-type E3 ubiquitin transferase makorin-1; RNF61
  • Host
    Rabbit
  • Protein IDQ9UHC7
  • Protein Name
    E3 ubiquitin-protein ligase makorin-1
  • Scientific Description
    Rabbit polyclonal to MKRN1.E3 ubiquitin-protein ligase makorin-1 (MKRN1) catalyzes the covalent attachment of ubiquitin moietiesonto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. MKRN1supports cell survival by suppressing p53/TP53 under normal conditions, but stimulates apoptosis byrepressing CDKN1A under stress conditions. MKRN1 acts as a negative regulator of telomerase andhas negative and positive effects on RNA polymerase II-dependent transcription.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203