ML-323 [1572414-83-5]

Biorbyt

ML-323 [1572414-83-5]

16

1572414-83-5

Research Use Only

C23H24N6

384.48

ML323 is a reversible, potent USP1-UAF1 inhibitor with IC50 of 76 nM in a Ub-Rho assay and 174 nM and 820 nM in orthogonal gel-based assays using K63-linked diubiquitin (di-Ub) and monoubiquitinated PCNA (Ub-PCNA) as substrates, respectively.

C(C1=CC=CC=C1C(C)C)1=NC=C(C)C(NCC2=CC=C(N3C=CN=N3)C=C2)=N1

12352200