ML381

MedChem Express

ML381

10

Research Use Only

98.0

C21H21N3O4

379.41

ML381 (VU0488130) is a highly selective, central nervous system penetrant mAChR M5 orthogonal antagonist ( IC 50 = 450 nM; Ki = 340 nM). ML381 is unstable in rat plasma and can be mainly used as a molecular probe for in vitro and electrophysiological studies [1] [2] .

O=C(C1=NOC(COC2=CC=CC(C(C)=O)=C2)=C1)N(C)[C@H](C3=NC=CC=C3)C

-20°C,2°C to 8°C

12352200