
Western blot analysis of extracts from HUVEC cells, using MLF1 antibody.
MLF1 Antibody
CSB-PA583476
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetMLF1
Overview
- SupplierCusabio
- Product NameMLF1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4291
- Target nameMLF1
- Target descriptionmyeloid leukemia factor 1
- Target synonymsmyelodysplasia-myeloid leukemia factor 1; myeloid leukemia factor 1; testis tissue sperm-binding protein Li 49e
- HostRabbit
- IsotypeIgG
- Protein IDP58340
- Protein NameMyeloid leukemia factor 1
- Scientific DescriptionInvolved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. Yoneda-Kato N., Oncogene 12:265-275(1996) [PubMed: 8570204]. Hanissian S.H., Oncogene 23:3700-3707(2004) [PubMed: 15116101]. Yoneda-Kato N., EMBO J. 24:1739-1749(2005) [PubMed: 15861129].
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203