MLKL Antibody, FITC conjugated

Cusabio

MLKL Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

MLKL

mixed lineage kinase domain like pseudokinase

hMLKL; mixed lineage kinase domain-like protein

Rabbit

IgG

Mixed lineage kinase domain-like protein

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Human

-20°C or -80°C

12352203