MLL2 antibody

Biorbyt

MLL2 antibody

16

Western Blot

WB:1:1000-1:5000 WB

Research Use Only

Polyclonal

Unconjugated

KMT2D

lysine methyltransferase 2D

AAD10; ALL1-related protein; ALR; CAGL114; histone-lysine N-methyltransferase 2D; histone-lysine N-methyltransferase MLL2; KABUK1; Kabuki make-up syndrome; Kabuki mental retardation syndrome; KMS; lysine (K)-specific methyltransferase 2D; lysine N-methyltransferase 2D; MLL2; MLL4; myeloid/lymphoid or mixed-lineage leukemia 2; TNRC21; trinucleotide repeat containing 21; truncated lysine methyltransferase 2D

Rabbit

Histone-lysine N-methyltransferase 2D

Rabbit polyclonal to MLL2.MLL2 is a histone methyltransferase that methylates Lys-4 of histone H3 (H3K4me). H3K4merepresents a specific tag for epigenetic transcriptional activation. MLL2 plays a central role in betaglobinlocus transcription regulation by being recruited by NFE2. MLLS acts as a coactivator forestrogen receptor by being recruited by ESR1, thereby activating transcription. MLL2 is also requiredduring the transcriptionally active period of oocyte growth for the establishment and/or maintenance ofbulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption ofmeiosis, oocyte survival and normal zygotic genome activation.

Human, Mouse

-20°C

12352203