
WB analysis of HL60 (A), A549 (B), NIH3T3 (C), H9C2 (D) whole cell lysates using GTX55187 MLL4 antibody.
MLL4 antibody
GTX55187
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetKMT2B
Overview
- SupplierGeneTex
- Product NameMLL4 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9757
- Target nameKMT2B
- Target descriptionlysine methyltransferase 2B
- Target synonymsCXXC10; DYT28; histone-lysine N-methyltransferase 2B; histone-lysine N-methyltransferase MLL4; HRX2; lysine (K)-specific methyltransferase 2B; mixed lineage leukemia gene homolog 2; MLL1B; MLL2; MLL4; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4; myeloid/lymphoid or mixed-lineage leukemia protein 4; trithorax homologue 2; TRX2; WBP7; WBP-7; WW domain binding protein 7
- HostRabbit
- IsotypeIgG
- Protein IDQ9UMN6
- Protein NameHistone-lysine N-methyltransferase 2B
- Scientific DescriptionThis gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Histone methylation and demethylation are implicated in the transient and sustained activation of the interleukin-1beta gene in murine macrophages. Imuta H et al., 2020 Dec, Heart VesselsRead more