Bio-Connect
WB analysis of HL60 (A), A549 (B), NIH3T3 (C), H9C2 (D) whole cell lysates using GTX55187 MLL4 antibody.
WB analysis of HL60 (A), A549 (B), NIH3T3 (C), H9C2 (D) whole cell lysates using GTX55187 MLL4 antibody.
WB analysis of HL60 (A), A549 (B), NIH3T3 (C), H9C2 (D) whole cell lysates using GTX55187 MLL4 antibody.

MLL4 antibody

GTX55187
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetKMT2B
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    MLL4 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID9757
  • Target name
    KMT2B
  • Target description
    lysine methyltransferase 2B
  • Target synonyms
    CXXC10; DYT28; histone-lysine N-methyltransferase 2B; histone-lysine N-methyltransferase MLL4; HRX2; lysine (K)-specific methyltransferase 2B; mixed lineage leukemia gene homolog 2; MLL1B; MLL2; MLL4; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4; myeloid/lymphoid or mixed-lineage leukemia protein 4; trithorax homologue 2; TRX2; WBP7; WBP-7; WW domain binding protein 7
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UMN6
  • Protein Name
    Histone-lysine N-methyltransferase 2B
  • Scientific Description
    This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Histone methylation and demethylation are implicated in the transient and sustained activation of the interleukin-1beta gene in murine macrophages. Imuta H et al., 2020 Dec, Heart Vessels
    Read more