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MLT-747 [2097853-86-4]

MLT-747 [2097853-86-4]

T16119
TargetMol Chemicals
CAS Number2097853-86-4
DownloadMSDS
Product group Chemicals
Molecular Weight478.33
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    MLT-747 [2097853-86-4]
  • Delivery Days Customer
    72
  • CAS Number
    2097853-86-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    MLT-747
  • Molecular Formula
    C20H21Cl2N7O3
  • Molecular Weight
    478.33
  • Scientific Description
    MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).
  • Shelf life instruction
    3 years
  • SMILES
    CO[C@@H](C)c1c(NC(=O)Nc2cnc(C(=O)N3CCCC3)c(Cl)c2)cnc2cc(Cl)nn12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Quancard J et al., 2019 Mar, Nat Chem Biol
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