MM-589 (TFA)

MedChem Express

MM-589 (TFA)

10

Research Use Only

98.67

C30H45F3N8O7

686.72

MM-589 TFA is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interaction. MM-589 binds to WDR5 with an IC 50 of 0.90 nM and inhibits the MLL H3K4 methyltransferase activity with an IC 50 of 12.7 nM [1] .

O=C(NCC[C@](NC(C(C)C)=O)(C)C1=O)[C@H](NC([C@@H](NC([C@H](CCCNC(NC)=N)N1)=O)CC)=O)C2=CC=CC=C2.FC(C(O)=O)(F)F

-20°C

12352200