MMP13 Polyclonal Antibody
RD82228A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetMMP13
Overview
- SupplierReddot Biotech
- Product NameMMP13 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4322
- Target nameMMP13
- Target descriptionmatrix metallopeptidase 13
- Target synonymsCLG3; collagenase 3; MANDP1; matrix metalloproteinase 13 (collagenase 3); MDST; MMP-13
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203