MMP25 Polyclonal Antibody
RD266614A
ApplicationsImmunoFluorescence, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMMP25
Overview
- SupplierReddot Biotech
- Product NameMMP25 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence, ImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID64386
- Target nameMMP25
- Target descriptionmatrix metallopeptidase 25
- Target synonymsleukolysin; matrix metallopeptidase-like 1; matrix metalloproteinase 20; matrix metalloproteinase-25; matrix metalloproteinase-like 1; membrane-type 6 matrix metalloproteinase; membrane-type matrix metalloproteinase 6; MMP20; MMP20A; MMP-25; MMPL1; MT6MMP; MT6-MMP; MT-MMP 6; MTMMP6; MT-MMP6
- HostRabbit
- IsotypeIgG
- Scientific DescriptionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203