MMV688533 [2260904-47-8]

MedChem Express

MMV688533 [2260904-47-8]

5

2260904-47-8

Research Use Only

99.72

C24H15F6N5O2

519.40

MMV688533 is an antimalarial agent with rapid anti-plasmodial activity and effective single-dose activity against Plasmodium falciparum infection in humanized mouse models. MMV688533 can inhibit the activity of asexual blood stage parasites with an IC50 value of 1.3 nM. MMV688533 exhibits excellent pharmacokinetic properties and safety[1].

O=C(C1=CC(C#CC2=CC=C(C(F)(F)F)C(C(NC3=NC=CC=C3)=O)=C2)=CC(C(F)(F)F)=C1)NC(N)=N

-20°C,2°C to 8°C

12131703