Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Jurkat cells, K562 cells, Primary antibody: CSB-PA788447(MOB1B Antibody) at dilution 1/112.5, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Jurkat cells, K562 cells, Primary antibody: CSB-PA788447(MOB1B Antibody) at dilution 1/112.5, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
MOB1B Antibody
CSB-PA788447
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetMOB1B
Overview
- SupplierCusabio
- Product NameMOB1B Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID92597
- Target nameMOB1B
- Target descriptionMOB kinase activator 1B
- Target synonymsMATS2; MOB kinase activator 1B; mob1 homolog 1A; MOB1 Mps One Binder homolog B; MOB1, Mps One Binder kinase activator-like 1A; mob1A; MOB4A; MOBKL1A; mps one binder kinase activator-like 1A
- HostRabbit
- IsotypeIgG
- Protein IDQ7L9L4
- Protein NameMOB kinase activator 1B
- Scientific DescriptionThe protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene. Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203