Western blot analysis of extracts from 293 cells, COS-7 cells and HUVEC cells all treated with IFN (2500U/ml, 30mins), using MOL1A antibody.
Western blot analysis of extracts from 293 cells, COS-7 cells and HUVEC cells all treated with IFN (2500U/ml, 30mins), using MOL1A antibody.
MOB1B Antibody
CSB-PA970943
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetMOB1B
Overview
- SupplierCusabio
- Product NameMOB1B Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID92597
- Target nameMOB1B
- Target descriptionMOB kinase activator 1B
- Target synonymsMATS2; MOB kinase activator 1B; mob1 homolog 1A; MOB1 Mps One Binder homolog B; MOB1, Mps One Binder kinase activator-like 1A; mob1A; MOB4A; MOBKL1A; mps one binder kinase activator-like 1A
- HostRabbit
- IsotypeIgG
- Protein IDQ7L9L4
- Protein NameMOB kinase activator 1B
- Scientific DescriptionActivator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L. Florindo C.S., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases The MGC Project Team, Genome Res. 14:2121-2127(2004). Devroe E., J. Biol. Chem. 279:24444-24451(2004).
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203