Molidustat sodium [1375799-59-9]

TargetMol Chemicals

Molidustat sodium [1375799-59-9]

9

1375799-59-9

Research Use Only

C13H13N8NaO2

336.28

Molidustat sodium (5 microM; 20 min) is sufficient to induce detectable levels of HIF-1alpha in HeLa cells. In a cellular reporter assay, the compound stimulates the expression of the luciferase reporter gene under the control of a hypoxia-responsive element promoter, with an average (+/- SD) EC50 of 8.4 microM (n=4).

[Na].OC1=C(C=NN1C2=NC=NC(=C2)N3CCOCC3)N4N=NC=C4

-20°C

12352200