Momelotinib (sulfate)

MedChem Express

Momelotinib (sulfate) [1056636-06-6]

10

1056636-06-6

Research Use Only

98.06

C23H26N6O10S2

610.62

Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC 50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC 50 =155 nM).

O=C(NCC#N)C(C=C1)=CC=C1C2=NC(NC(C=C3)=CC=C3N4CCOCC4)=NC=C2.O=S(O)(O)=O.O=S(O)(O)=O

2°C to 8°C

12352200