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Monastrol [329689-23-8]

Research Use Only
ORB146117
Biorbyt
CAS Number329689-23-8
Product group Chemicals
Molecular Weight292.4
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Monastrol [329689-23-8]
  • Delivery Days Customer
    16
  • CAS Number
    329689-23-8
  • Certification
    Research Use Only
  • Molecular Formula
    C14H16N2O3S
  • Molecular Weight
    292.4
  • Scientific Description
    Monastrol is a reversible, cell-permeable inhibitor of the motor protein Eg5 (kinesin family protein 11, Kif11), blocking basal ATPase activity in vitro (IC50 = 6.1 microM) and inducing the formation of monoastral spindles in cell-based assays (IC50 = 51.3 microM
  • SMILES
    S=C1NC(C2=CC(O)=CC=C2)C(C(OCC)=O)=C(C)N1
  • UNSPSC
    12352200

References

  • An Attachment-Independent Biochemical Timer of the Spindle Assembly Checkpoint. Qian J et al., 2017 Nov 16, Mol Cell
    Read more