Monomethyl auristatin E (MMAE, vedotin)
ORB180827
Overview
- SupplierBiorbyt
- Product NameMonomethyl auristatin E (MMAE, vedotin) [474645-27-7]
- Delivery Days Customer16
- CAS Number474645-27-7
- CertificationResearch Use Only
- Molecular FormulaC39H67N5O7
- Molecular Weight717.9785912
- Scientific DescriptionMonomethyl auristatin E (MMAE; Vedotin) is a hot topic in Antibody-drug conjugates (ADCs) studies. It is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin.
- SMILESCN[C@H](C(N[C@H](C(N(C([C@@H](CC(N1CCC[C@H]1[C@@H]([C@H](C(N[C@@H]([C@H](C1C=CC=CC=1)O)C)=O)C)OC)=O)OC)[C@H](CC)C)C)=O)C(C)C)=O)C(C)C
- UNSPSC12352200