Motesanib
ORB401974
CAS Number453562-69-1
Product group Chemicals
Molecular Weight373.46
Overview
- SupplierBiorbyt
- Product NameMotesanib [453562-69-1]
- Delivery Days Customer16
- CAS Number453562-69-1
- CertificationResearch Use Only
- Molecular FormulaC22H23N5O
- Molecular Weight373.46
- Scientific DescriptionMotesanib is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is appr 10-fold more selective for VEGFR than PDGFR and Ret.
- SMILESO=C(C1=CC=CN=C1NCC2=CC=NC=C2)NC3=CC(NCC4(C)C)=C4C=C3
- UNSPSC12352200