MOTS-c (human) [1627580-64-6]

AdipoGen Life Sciences

MOTS-c (human)

10

1627580-64-6

Research Use Only

>95%

C101H152N28O22S2 . C2HF3O2

2174.6 . 114.0

Chemical. CAS: 1627580-64-6. Formula: C101H152N28O22S2 . C2HF3O2. MW: 2174.6 . 114.0. Synthetic. Mitochondria-derived peptide (MDP). Promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK). Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in mice. Potential anti-obesity and anti-aging compound. - Mitochondria-derived peptide (MDP). Promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK). Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in mice. Potential anti-obesity and anti-aging compound. Involved in cellular stress resistance by regulating the nuclear genome. During metabolic stress (serum or glucose deprivation or oxidative stress) translocates to the nucleus in an AMPK-dependent manner. In the nucleus, MOTS-c binds to the transcription factor NRF2 that is a stress-responsive transcription factor and activates anti-oxidative stress genes.

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-20°C,2°C to 8°C

12352200