Mouse 4-1BB Ligand, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Mouse 4-1BB Ligand / TNFSF9 Protein, Fc Tag
41L-M5257
Overview
- SupplierACRObiosystems
- Product NameMouse 4-1BB Ligand / TNFSF9 Protein, Fc Tag
- Delivery Days Customer4
- Category SupplierImmune Checkpoint Proteins
- CertificationResearch Use Only
- ConjugateUnconjugated
- Estimated Purity95%
- FormatPowder
- Molecular Weight49.0 kDa
- Scientific DescriptionCharacteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49.0 kDa. The protein migrates as 64-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Description: Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
- Shelf life instruction● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- SourceMouse 4-1BB Ligand, Fc Tag (41L-M5257) is expressed from human 293 cells (HEK293). It contains AA Arg 104 - Glu 309 (Accession # NP_033430).
- ReactivityMouse
- Reactivity SupplierMouse
- Reactivity Supplier NoteC-Fc. HEK293. Arg 104 - Glu 309
- Storage Instruction-20℃
- UNSPSC12352202