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Mouse AMIGO2 Protein (AMI-MM102)

AMI-MM102
KACTUS
Protein IDQ80ZD9
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    KACTUS
  • Product Name
    Mouse AMIGO2 Protein (AMI-MM102)
  • Delivery Days Customer
    9
  • Estimated Purity
    >95%
  • Formulation
    Lyophilized
  • Protein IDQ80ZD9
  • Protein Name
    Amphoterin-induced protein 2
  • Scientific Description
    Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BETi and identified AMIGO2, a transmembrane molecule, as a BET target gene essential for melanoma cell survival. AMIGO2 is upregulated in melanoma cells and tissues compared to human melanocytes and nevi, and AMIGO2 silencing in melanoma cells induces G1/S arrest followed by apoptosis.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202