Mouse anti Human p53 (a.a. 16-25)
X1157M
ApplicationsImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Xenopus
TargetTP53
Overview
- SupplierNordic-MUbio
- Product NameMouse anti Human p53 (a.a. 16-25)
- Delivery Days Customer7
- Application Supplier NoteDetects p53 protein by Western blot at 1 to 10 microg/ml. Detects a band a approximately 53 kDa in HCT116 cell lysate. Optimal concentration should be evaluated by serial dilutions.
- ApplicationsImmunoPrecipitation, Western Blot, ELISA
- Applications SupplierWestern Blotting;ELISA;Immunoprecipitation
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDX77
- ConjugateUnconjugated
- Gene ID7157
- Target nameTP53
- Target descriptiontumor protein p53
- Target synonymsantigen NY-CO-13; BCC7; BMFS5; cellular tumor antigen p53; LFS1; mutant tumor protein 53; P53; p53 tumor suppressor; phosphoprotein p53; transformation-related protein 53; TRP53; tumor protein 53; tumor supressor p53
- HostMouse
- IsotypeIgG1
- Protein IDP04637
- Protein NameCellular tumor antigen p53
- Shelf life instructionSee expiration date on vial
- SourceHybridoma produced by the fusion of splenocytes from mice immunized with full length Xenopus p53 protein and mouse myeloma cells.
- ReactivityHuman, Mouse, Xenopus
- Reactivity SupplierHuman;Mouse;Xenopus
- UNSPSC12352203
References
- 1. Zeng, X., et al. UV but not gamma irradiation accelerates p53-induced apoptosis of teratocarcinoma cells by repressing MDM2 transcription. Cancer Res. 2000, 60, 6184-6188 2. Hussain, S.P., et al. p53 tumor suppressor gene: at the crossroads of molecular carcinogenesis, molecular epidemiology and human risk assessment. Ann. N.Y. Acad. Sci. 2000, 919, 7985 3. Hellin, A.C., et al. Roles of Nuclear Factor-kappaB, p53 and p21/WAF1 in Daunomycin-induced cell cycle arrest and apoptosis. J. Pharmacol. Exp. Ther. 2000, 295, 870-878 4. Portefaix, J.M., et al. 'Critical residues of epitopes recognized by several anti-p53 monoclonal antibodies correspond to key residues of p53 involved in interactions with the mdm2 protein.' J. Immunol. Methods. 2000, 244(1-2), 17-28.