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ProductsBack/Mouse anti Human Sphingosine 1 Phosphate 4 Receptor (CT) (EDG6), conjugated with FITC

Mouse anti Human Sphingosine 1 Phosphate 4 Receptor (CT) (EDG6), conjugated with FITC

Research Use Only
X1626M
Nordic-MUbio
ApplicationsFlow Cytometry, Western Blot
Product group Antibodies
ReactivityHuman
TargetS1PR4
Price on request
100 ug
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Overview

  • Supplier
    Nordic-MUbio
  • Product Name
    Mouse anti Human Sphingosine 1 Phosphate 4 Receptor (CT) (EDG6), conjugated with FITC
  • Delivery Days Customer
    7
  • Application Supplier Note
    The X1626M antibody can be used for flow cytometry (use 1 microg of antibody per 106 cells). NOTE: Epitope for the antibody is the C-terminal region of the EDG6 protein. The C-terminus is an intracellular region and cells need to be permeablized prior to staining with antibody. Optimal concentration should be evaluated by serial dilutions.
  • Applications
    Flow Cytometry, Western Blot
  • Applications Supplier
    Western Blotting;Flow Cytometry
  • Category Supplier
    Primary antibodies
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1
  • Conjugate
    FITC
  • Gene ID8698
  • Target name
    S1PR4
  • Target description
    sphingosine-1-phosphate receptor 4
  • Target synonyms
    EDG6; endothelial differentiation G-protein coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6; LPC1; S1P receptor 4; S1P receptor Edg-6; S1P4; SLP4; sphingosine 1-phosphate receptor 4; sphingosine 1-phosphate receptor Edg-6
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDO95977
  • Protein Name
    Sphingosine 1-phosphate receptor 4
  • Scientific Description
    Endothelial cell differentiation gene 6 C-terminal; Sphingosine-1-Phosphate Receptor-4 (S1P4)
  • Shelf life instruction
    See expiration date on vial
  • Source
    Hybridoma produced by the fusion of splenocytes from mice immunized with a unique synthetic peptide derived from the C-terminal region of the EDG6 (S1P4) protein and mouse myeloma cells.
  • Reactivity
    Human
  • Reactivity Supplier
    Human
  • UNSPSC
    12352203

References

  • 1. Yamazaki, Y., et al. 'EDG-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway.' Biochem. Biophys. Res. Commun. 2000, 268, 583-589. 2. Van Brocklyn, J.R., et al. 'Sphingosine 1-phosphate is a ligand for the G protein-coupled receptor EDG-6.' Blood 2000, 95, 2624-2629. 3. Takuwa, Y., et al. 'Subtype-specific, differential activities of the EDG family receptors for sphingosine 1-phosphate, a novel lysophospholipid mediator.' Mol. Cell Endocrinol. 2001, 177, 3-11. 4. Ohotski, J., et al. Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer. Br. J. Can. (2012), 106, 1453-1459