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Mouse CD38 protein

Research Use Only
ORB511244
Biorbyt
Product group Molecular Biology
Price on request
Packing Size
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Mouse CD38 protein
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Scientific Description
    CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116133