Mouse Factor H/CFH Protein (CFH-MM101)
CFH-MM101
Product group Proteins
Overview
- SupplierKACTUS
- Product NameMouse Factor H/CFH Protein (CFH-MM101)
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity>95%
- Scientific DescriptionFactor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self) can hijack factor H to evade the immune response.
- Storage Instruction-20°C or -80°C,-80°C
- UNSPSC12352202