Mouse IgG3 isotype control [B10] (PE)
GTX35030
Overview
- SupplierGeneTex
- Product NameMouse IgG3 isotype control [B10] (PE)
- Delivery Days Customer9
- Application Supplier NoteUse at a concentration/dilution equivalent to that of your experimental primary antibody.
- ApplicationsFlow Cytometry, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDB10
- ConjugateRPE
- HostMouse
- IsotypeIgG3
- Scientific DescriptionInclusion of an appropriate isotype control is essential for the proper interpretation of experimental results. Because isotype control antibodies have no relevant specificity, they enable the researcher to distinguish non-specific background binding from antigen-specific antibody binding. Non-specific binding of primary antibodies may occur due to either binding of antibody to Fc receptors or non-specific interactions with cellular proteins, lipids, or carbohydrates. Additionally, autofluorescence or endogenous enzyme activity in target cells may give a false positive that could be misinterpreted as antibody binding. These factors vary by target cell type and the isotype of the primary antibody. Therefore, the primary antibody used should be matched to an isotype control of identical species and isotype (including both heavy and light chains).
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Helicobacter pylori Neutrophil-Activating Protein Directly Interacts with and Activates Toll-like Receptor 2 to Induce the Secretion of Interleukin-8 from Neutrophils and ATRA-Induced Differentiated HL-60 Cells. Wen SH et al., 2021 Oct 26, Int J Mol SciRead more
- Gain of function in the immune system caused by a ryanodine receptor 1 mutation. Vukcevic M et al., 2013 Aug 1, J Cell SciRead more