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Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein (ITG-MM1A1)

ITG-MM1A1
KACTUS
Protein IDQ3V3R4
Product group Proteins
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Overview

  • Supplier
    KACTUS
  • Product Name
    Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein (ITG-MM1A1)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Protein IDQ3V3R4
  • Protein Name
    Integrin alpha-1
  • Scientific Description
    Integrin alpha1beta1 is a heterodimer of the Integrin subunits alpha 1 and beta 1 and is one of four collagen-binding integrins, it preferentially binds Collagens I, IV, VI, XIII and XVI, but also binds Laminin. Integrin alpha1beta1 is widely expressed in mesenchyme and the immune system, as well as a minority of epithelial tissues. It can suppresse EGFR signaling, increase expression of Caveolin-1, reduce production of reactive oxygen species, regulate collagen expression, regulate MMP collagenase and gelatinase activity, and mediates the renal basement membrane disorder Alport syndrome.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202