Mouse LRRN1 Protein (LNR-MM101)

KACTUS

Mouse LRRN1 Protein (LNR-MM101)

9

Research Use Only

>95%

Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction between midbrain and hindbrain compartments. Lrrn1 also regulates the glycosyltransferase Lunatic Fringe, a modulator of Notch signalling, maintaining its expression in midbrain cells which is instrumental in MHB boundary formation.

-20°C or -80°C,-80°C

12352202