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Mouse MARCO Protein (Recombinant 8His, N-terminus)

Research Use Only
LS-G137905
LifeSpan BioSciences
Product group Proteins / Signaling Molecules
Price on request
Packing Size
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Overview

  • Supplier
    LifeSpan BioSciences
  • Product Name
    Mouse MARCO Protein (Recombinant 8His, N-terminus)
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Scientific Description
    MARCO (macrophage receptor with collagenous structure) is an 80 kDa type II transmembrane glycoprotein that belongs to the class A scavenger receptor family. Mouse MARCO consists of a 48 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 449 aa extracellular domain (ECD) that includes a stalk region, a collagenlike region, and one SRCR domain. MARCO is constitutively expressed on the surface of splenic and lymph node macrophages. MARCO binds LPS, lipoteichoic acid, and other determinants on Gram positive and Gram negative bacteria. It also binds modified LDL, CpG oligonucleotides, UGRP1, silica, and TiO2.
  • Storage Instruction
    2°C to 8°C,-20°C,RT
  • UNSPSC
    12352202